The digestive tract in a human body is shelter to a number of different bacteria strains. Many of these are advantageous, while others add to health issues such as inflammatory bowel disease. Scientists from the Broad Institute and MIT have now preserved and isolated samples of almost 8,000 of these strains, while also explaining their metabolic and genetic context.
This data set, which is accessible to other scientists who wish to employ it, might assist to shed light on the microbial populations’ dynamics in the human body and might assist researchers design new methods to cure a series of diseases, claims Eric Alm.
“There is a lot of enthusiasm in the microbiome field since there are links between health & disease and these bacteria. But we are falling short in being capable of understanding why that is, what are the roles of those bacteria that are leading them to associate with disease, and what’s the mechanism,” claims senior author of the research, Alm, to the media. The researchers gathered stool samples from almost 90 individuals for the study.
On a related note, the University of Oregon researchers have disclosed a molecular method by which Helicobacter pylori (the human stomach pathogen) is drawn to bleach, also known as HOCI or hypochlorous acid. The research disclosed that H. pylori employs a protein dubbed as TlpD to detect bleach and get towards it, and that the bacteria Escherichia coli and Salmonella enterica can utilize TlpD-akin proteins to identify bleach in the surrounding.
The scientists propose H. pylori employ the protein TlpD to sense locations of tissue inflammation, which can assist the bacteria inhabit the stomach and maybe locate damaged nutrients and tissue. The research, “Helicobacter pylori senses bleach (HOCI) as a chemoattractant using a cytosolic chemoreceptor,” is posted in the PLOS Biology journal.
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