Two famous and used antibiotics when united were found to be more efficient against lethal bacteria named Pseudomonas aeruginosa, which is a widespread reason for hospital-based infections. This latest study was carried out by a research team at Louis Stokes Cleveland VA Medical Center and Case Western Reserve University School of Medicine. This study is open for access in the Journal of Infectious Diseases.
This research is named as “Ceftazidime-Avibactam in Combination with Fosfomycin: A Novel Therapeutic Strategy against Multidrug-Resistant Pseudomonas aeruginosa.” The research team employed ceftazidime–avibactam, which is a blend that is being employed against critical bacterial infection, and fosfomycin, which is used while treating urinary tract infections. The latest combination was used on mice models with Pseudomonas infections. The results of this research showed that the blend was more efficient in killing the bacteria compared to either antibiotic alone.
On a similar note, a study by scientists into why a few bacteria have various shapes has discovered that a curved shape can make it simpler for them to find food. The findings of this research pose questions regarding whether disease-triggering bacteria have diverse shapes.
Life Sciences scientists from the University of Lincoln carried out computer simulations. They compared the swimming patterns of differently shaped bacteria. The results of this trial highlighted that a curved shape can be helpful for efficient swimming and for finding food via the employment of chemical trails (named as chemotaxis). But, this is possible at the cost of increased cell construction costs. This shows that a few bacteria species might balance the benefits and cost of their shape, dependent on their activity levels and environment. Earlier, it has not been comprehended what determines the diverse shapes of bacteria. The shape of big creatures is determined by the effects of gravity and streamlining. At the same time, for microscopic organisms, these don’t have such an impact.
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